Kobcinta Daryeelka Bukaanka ee hagaajinta Attenuation-ku Salaysan ee PET Imaging

Daraasad cusub oo cinwaan looga dhigay "Ka faa'iidaysiga Pix-2-Pix GAN ee Waxbarasho-Qoto-salaysan ee Jirka oo Dhan ee PSMA PET/CT Attenuation Correction" ayaa dhawaan lagu daabacay Volume 15 ee Oncotarget May 7, 2024.

Soo-gaadhista shucaaca ee daraasadaha PET/CT ee isdaba jooga ah ee dabagalka bukaanka kansarka waa walaac. Baaritaankii ugu dambeeyay, koox cilmi-baarayaal ah oo ay ku jiraan Kevin C. Ma, Esther Mena, Liza Lindenberg, Nathan S. Lay, Phillip Eclarinal, Deborah E. Citrin, Peter A. Pinto, Bradford J. Wood, William L. Dahut, James L. Gulley, Ravi A. Madan, Peter L. Choyke, Ismail Baris Turkbey, iyo Stephanie A. Harmon oo ka socda Machadka Qaranka ee Kansarka ee Machadyada Qaranka ee Caafimaadka ayaa soo bandhigay qalab sirdoon macmal ah (AI). Qalabkani waxa uu rajeenayaa in uu soo saaro sawiro la saxay PET (AC-PET) muuqaalada PET (NAC-PET) ee aan la saxin, taas oo suurtogal ah in ay yarayso baahida loo qabo baarista CT-ga ee qiyaas yar.

"Sawirrada PET-ka ee ay soo saartay Ai waxay leeyihiin awood caafimaad si ay u yareeyaan baahida loo qabo sixitaanka baarista CT-ga iyadoo la ilaalinayo calaamadaha tirada iyo tayada sawirka bukaannada kansarka qanjirka 'prostate'."

Hababka: Algorithm barasho qoto dheer oo ku salaysan 2D Pix-2-Pix naqshadaynta hal-abuurka adversarial network (GAN) ayaa la sameeyay iyadoo lagu salaynayo sawirada AC-PET iyo NAC-PET. 18F-DCFPyL PSMA (Prostate-specific membrane antigen) PET-CT ee 302 bukaan oo qaba kansarka qanjirka 'prostate' ayaa loo qaybiyay tababar, ansaxinta, iyo kooxaha baaritaanka (n 183, 60, iyo 59, siday u kala horreeyaan). Qaabka waxaa lagu tababaray iyadoo la adeegsanayo laba xeeladood oo la habeeyey: Standard Uptake Value (SUV) ku salaysan iyo SUV-NYUL ku salaysan. Baadhitaanka waxqabadka toosan ayaa lagu qiimeeyay iyadoo la isticmaalayo qalad labajibbaaran oo caadi ah (NMSE), micnaha khaladka saxda ah (MAE), tusaha isu ekaanshaha qaabdhismeed (SSIM) iyo saamiga ugu sarreeya ee signal-to-coise (PSNR). Dhakhtarka dawada nukliyeerka ayaa si rajada ah u sameeyay falanqaynta heerka dhaawaca ee aagga xiisaha. Tilmaamayaasha SUV waxaa lagu qiimeeyay iyadoo la adeegsanayo iskuxiraha koox-kooxaha (ICC), iskuxirnaanta soo noqnoqda (RC), iyo moodooyinka saamaynta isku dhafan ee tooska ah.

Natiijooyinka：Kooxda imtixaanka madaxa banaan, dhexdhexaadka NMSE, MAE, SSIM, iyo PSNR waxay ahaayeen 13.26%, 3.59%, 0.891, iyo 26.82, siday u kala horreeyaan. ICC ee SUVmax iyo SUVmean waxay ahaayeen 0.88 iyo 0.89, taas oo muujinaysa xidhiidh adag oo u dhexeeya calaamadaha sawirka asalka ah iyo AI-soo saaray. Qodobbada sida goobta dhaawaca, cufnaanta (cutubyada Hounsfield), iyo kor u qaadista nabarrada ayaa la ogaaday inay saameeyaan khaladka qaraabada ah ee cabbirada SUV ee la soo saaray (dhammaan p <0.05).

"AC-PET-ka ay soo saartay qaabka Pix-2-Pix GAN wuxuu muujinayaa qiyaasaha SUV ee si dhow ula socda sawirada asalka ah. Sawirada PET ee ay AI soo saartay waxay muujinayaan rajo caafimaad oo rajo leh oo lagu dhimayo baahida CT scans ee sixitaanka iyadoo la ilaalinayo calaamadaha tirada iyo tayada sawirka.

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Sida aynu wada ognahay, horumarinta warshadaha sawir-qaadista caafimaadku waa mid aan kala go 'lahayn horumarinta qalabyo caafimaad oo taxane ah - cirbadaha wakiilka ka soo horjeeda iyo adeegyadooda taageeraya - kuwaas oo si ballaaran loo isticmaalo goobtan. Dalka Shiinaha oo caan ku ah warshadaha wax soo saarka, waxa jira warshado badan oo dalka iyo dibaddaba caan ku ah soo saarista qalabka sawir-caafimaad ee ay ka mid yihiin.LnkMed. Tan iyo markii la aasaasay, LnkMed wuxuu xoogga saarayay garoonka duritaanka wakiilada isbarbardhigga cadaadiska sare. Kooxda injineernimada ee LnkMed waxaa hogaaminaya Ph.D. waayo-aragnimo ka badan toban sano oo si qoto dheer ugu hawlan cilmi-baarista iyo horumarinta. Isaga oo hagaya, eeCT hal madax isku duro,CT duri madax labalaab ah,duritaanka wakiilka isbarbardhigga MRIiyoAngiography-cadaadiska sare ee duritaanka wakiilkawaxaa loogu talagalay sifooyinkan: jirka xooggan oo is haysta, interface ku habboon oo caqli-gal ah, hawlaha dhamaystiran, badbaadada sare, iyo naqshad waara. Waxaan sidoo kale ku siin karnaa saliingooyin iyo tuubo ku habboon noocyada caanka ah ee CT, MRI, DSA durida iyagoo leh dabeecadooda daacadda ah iyo xoogga xirfadeed, dhammaan shaqaalaha LnkMed waxay si daacad ah kuugu martiqaadayaan inaad timaaddo oo aad sahamiso suuqyo badan si wadajir ah.